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This absence of formal research means that any combined use is based on extrapolation from individual drug studies, theoretical pharmacology, and anecdotal clinical experience rather than robust evidence

It is primarily used for the localized treatment of Fibromyalgia, Neuropathic Pain, Muscle Spasms, Arthritis, and Tendonitis

This is where a lot of people quietly get confused

Several studies have implied that FXR activation relieves intestinal inflammatory state in IBD patients, as well as that colonic inflammation in patients with CD and in rodent models of colitis is linked to diminished expression of FXR mRNA (Vavassori et al., 2009)