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Dr Carina Kern, lead author of the paper, explained: The body functions as an interconnected network, and the success of GLP-1s shows what happens when you target the system rather than the symptom. The authors propose developing precision systemic therapies that mimic the multi-organ benefits of GLP-1s while maintaining biological balance

Once intact bacteria and other antigenic substances cross the intestinal wall, they encounter numerous immune cells that react to these substances, leading to inflammation

doi: 10.3892/ijo.2023.5604 108 ZhangLZhangJXuanXWuDYuJWangPet al

Research involving incretin-based therapies has shown reductions in: waist circumference, visceral fat, liver fat, and total body fat percentage