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Targeting oxidative stress and metal homeostasis 7.4.1

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In this phase II trial involving 50 men with metastatic castration-resistant prostate cancer (mCRPC), the administration of docetaxel combined with oral curcumin (6 g/day for 7 days every 3 weeks) demonstrated no significant differences in progression-free survival (PFS), PSA response, overall survival, or quality of life (QoL) when compared with placebo, despite high compliance and confirmed curcumin absorption

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It can promote the differentiation and maturation of immune cells, modulate cytokine production, and contribute to wound healing and tissue repair (van Harten et al., 2018)

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