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These processes, in turn, decrease insulin-stimulated IRS-1/IRS-2 tyrosine phosphorylation, PI3K activation and downstream insulin signaling that then induces IR in muscles and livers
Granata A, Maccarrone R, Anzaldi M, Leonardi G, Pesce F, Amico F et al (2022) GLP-1 receptor agonists and renal outcomes in patients with diabetes mellitus type 2 and diabetic kidney disease: state of the art
We also calculated a complex patient scoring adjustment, described in section III.C.2.e.(3)
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