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The researchers believe that the extra weight loss could be attributed to how tirzepatide activated two metabolic receptors, rather than just the single one that semaglutide activates

The SmPC advises patients to seek immediate medical attention if experiencing persistent, severe abdominal pain, often radiating to the back, accompanied by nausea and vomiting

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What the clinical trials do show is how tirzepatide performs at standard and higher doses, which gives us a framework for understanding what lower doses might achieve