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Theyve been on the market for a while, but theyve gotten really hot for weight loss over the last couple of years, explains Ryan McSpadden, MD, a Head & Neck / Plastic and Reconstructive surgeon at Roswell Park Comprehensive Cancer Center

Whilst Rybelsus has a low intrinsic risk of hypoglycaemia due to its glucose-dependent mechanism of action, the risk increases when used in combination with insulin or sulfonylureas

Nevertheless, clinicians should continue following established precautions and reviewing patient history before initiating therapy

Seek urgent medical assistance if you develop: severe and persistent abdominal pain repeated vomiting or inability to keep fluids down swelling of the face, lips, tongue or throat difficulty breathing severe dizziness, confusion or fainting sudden loss or rapid deterioration of vision symptoms of severe low blood sugar when using insulin or a sulphonylurea Suspected adverse reactions can also be reported through the MHRA Yellow Card scheme