There are two reasons people become deficient in vitamin B12: They dont eat the proper foods or take supplements Their bodies cant absorb enough B12, no matter how many good foods or supplements they consume When someone lacks the right amount of vitamin B12, they usually start to develop the following symptoms: Anaemia Difficulty walking properly Cognitive issues (struggling to think clearly, for example) Fatigue Constipation Irritability Changes in vision Numbness and/or tingling in the feet, legs, and hands An inflamed tongue Any of these can interfere with your quality of life and impair your most basic functions

The following primary antibodies and their dilutions were used: anti-Gstt1 (Abcam, ab175418, 1:200 for mouse and human tissues), anti-TromaIII (DSHB, 1:500, for mouse tissues), anti-Cytokeratin (Dako, M351529-2, 1:500, for human tissues), Cytokeratin19-555 (Abcam, 203444, 1:500, for human tissues), anti-PCNA (PC10) (Santa Cruz, sc-56, 1:200, for mouse tissues), anti-Ki67 (Abcam, 1:200, for human tissues), and anti-Fibronectin (Santa Cruz, 271098, 1:200, for mouse and human tissues)
In lung cancer, spermidine/spermidine N1-acetyltransferase 1 (SAT1) serves as a rate-limiting enzyme in polyamine catabolism
Ther Deliv