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Other mechanisms include increased insulin resistance induced by high-dose glucocorticoids that increases intra-portal insulin, decreases IGFBP-1 that increases free IGF-I, and direct glucocorticoid effects in increasing hepatic IGF-I synthesis and decreasing hepatic insulin clearance (105)

Reparao de tendes e ligamentos Em estudos pr-clnicos sobre modelos de leses tendneas (tendo de Aquiles, manguito rotador), o BPC-157 acelerou a cicatrizao ao aumentar a proliferao dos fibroblastos tendneos e a sntese de colgeno, com uma melhora mensurvel das propriedades biomecnicas do tecido reparado

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