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The development of indeterminate symbiotic nodules (with prolonged meristem activity) involves processes such as root hair deformations, infection thread growth, the reactivation of cell division in the root inner cortex and pericycle followed by nodule primordium development, bacterial release, the differentiation of infected cells associated with repeated rounds of endoreduplication, and the differentiation of bacteria into nitrogen-fixing bacteroids (Tsyganova et al., 2018)

however, the specific mechanisms of action remain poorly understood

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Circulating Tumor DNA-Defined Minimal Residual Disease in Solid Tumors: Opportunities to Accelerate the Development of Adjuvant Therapies