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Separate ex vivo and in vitro studies suggest that combining GHK-Cu with hyaluronic acid, especially lower-molecular-weight fractions at specific ratios, may further support collagen IV presence at the dermalepidermal junction

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Compression-induced invasion and migration of breast cancer cells are attributed to the activation of the MIC Piezo 1 [121] and the formation of leader cells, which possess filopodia at their leading-edge, thereby driving persistent and directional motility [120]