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However, when catalase activity decreases, hydrogen peroxide accumulates and directly attacks tyrosinase, a key enzyme in melanin synthesis

doi: 10.1128/spectrum.01639-23 176 PooleJ.FosterE.ChalonerK.HuntJ.JenningsM

3.2 Gastrointestinal barriers The intestinal epithelium is a single layer of cells lined the gut lumen that acts as a barrier to prevent injurious, intraluminal entities as well as microorganisms, toxins, foreign antigens, and allowing the translocation of essential electrolytes, dietary nutrients, and water from lumen into the circulation [16, 51, 72]

Oxidative stress in the cells was induced by tBuOOH in 0.11.5 mM concentrations