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Additionally, the commenter stated that in the CY 2026 OPPS/ASC proposed rule, CMS appropriately acknowledged that the LithoVue TM Elite Ureteroscope may fall within the scope of the existing device category C1747, which includes all single-use ureteroscopes and their associated procedures

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Like at AMYRs, these features require the expansion of extracellular TM bundle of CTR through outward movements of TM1, ECL1/TM3, TM4/ECL2 and a small shift in the positioning of the mid-region of the peptide at the start of the N-terminal helix, relative to rAmy when bound to the CTR in the bypass conformation (Fig