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While these medications work through separate pathways, their effects can overlap, particularly regarding appetite suppression and cardiovascular stimulation

Therefore, the interpretation of related findings should return to verifiable key variables, including dose and time window, tissue niche, cell lineage origin, as well as substrate competition and transporter expression levels ( From the perspective of the evidence hierarchy, current studies on amino acid metabolism-mediated regulation of macrophage polarization are still derived mainly from in vitro polarization models and animal experiments

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