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This modulation lowers systemic inflammation by increasing microbial diversity and inhibiting the proliferation of pathogenic species

In receptor binding studies, it has been shown to have a GLP-1R and GLP-1 binding affinity, respectively, about five times lower than that of native and similar to endogenous GIP (40)

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While these symptoms often improve over time as tolerance develops, rarely more serious gastrointestinal complications can occur that require prompt medical assessment