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Exploring use of unsupervised clustering to associate signaling profiles of GPCR ligands to clinical response

Both the internal training dataset and the out of sample testing dataset uses Neurocombat algorithm to harmonise the features

While Ex4 mildly reduced morphine-induced hyperlocomotion, it did not attenuate the expression of morphine-induced CPP, indicating a lack of effect on opioid reward in this model

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