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The association with autoimmune diseases increases with the severity of AD, particularly for conditions such as psoriatic arthritis, alopecia areata, and vitiligo (15, 16)

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The study demonstrated enhanced antibacterial effects, increased penetration into bacterial cells, and prolonged drug activity compared to its free form, making it a potential treatment for combating resistant bacterial infections and multidrug resistance [156]

Danuglipron increased insulin levels in primates but not rodents, which was explained by receptor mutagensis studies and a cryogenic electron microscope structure that revealed a binding pocket requiring a primate-specific tryptophan 33 residue