Vijiaratnam N, Girges C, Auld G, McComish R, King A, Skene SS, Hibbert S, Wong A, Melander S, Gibson R, Matthews H, Dickson J, Carroll C, Patrick A, Inches J, Silverdale M, Blackledge B, Whiston J, Hu M, Welch J et al (2025) Exenatide once a week versus placebo as a potential disease-modifying treatment for people with Parkinsons disease in the UK: a phase 3, multicentre, double-blind, parallel-group, randomised, placebo-controlled trial
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Excessive supplementation can cause nausea, vomiting, abdominal cramps, diarrhoea, fishy skin, muscle weakness in people with uremia and seizure disorders in people with seizure disordersand
High quality studies are needed before solid conclusions can be reached about the long-term safety of these supplements