Studies in obese rodents fed high-fat diets for extended periods show that diminished carnitine reserves in skeletal muscle are accompanied by marked perturbations in mitochondrial fuel metabolism, including reduced complete fatty acid oxidation, elevated incomplete -oxidation, and impaired substrate switching from fatty acid to pyruvate oxidation
Functional health experts, supplement manufacturers and health and fitness influencers are promoting this supplement for its potential to help transport more fat into muscle cells to produce more energy, which burns more fat in the process
Creatine: Protecting Brain Energetics After Injury Creatine, commonly associated with muscular performance, also plays a pivotal role in brain energy homeostasis
[PubMed] [Google Scholar] Willekens H., Chamnongpol S., Davey M., Schraudner M., Langebartels C., Van Montagu M., Inz D., Van Camp W