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This oxidative stress can activate classical apoptotic pathways, a process termed copper-induced apoptosis, which is mediated by DNA/membrane damage and the caspase/Bcl-2/p53 pathway and can be inhibited by caspase inhibitors [7]

HG also induced epithelial-mesenchymal transition (EMT) and upregulated fibrosis-related genes, suggesting that HG-induced EMT contributes to subretinal fibrosis, the end-stage of eye diseases, including proliferative DR

Ask your provider to explain their rationale for the injectable route versus topical if you are offered an injectable protocol for hair goals

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