Infections: vulvovaginal candidiasis, bacterial vaginosis, vulvovaginitis Comparative observational signal (protective association): In a phenome-wide association study comparing people with type 2 diabetes prescribed GLP-1 receptor agonists vs SGLT2 inhibitors and DPP4 inhibitors (NIH All of Us cohort, Jan 2018Oct 2023), semaglutide prescription was associated with reduced risk of diagnoses including candidiasis of vulva and vagina and inflammatory disease of cervix, vagina, and vulva compared with SGLT2 inhibitors
For many people, this is exactly what theyve been needing for years
Slowed Stomach Emptying: GLP-1 slows the rate at which your stomach empties, keeping you fuller for longer and leading to a gradual rise in blood sugar after eating
patients should report right upper quadrant pain, fever, or jaundice Diabetic retinopathy complications : Rapid glycemic improvement may temporarily worsen retinopathy in susceptible patients Acute kidney injury : Usually secondary to dehydration from gastrointestinal side effects Hypoglycemia : Particularly when combined with insulin or sulfonylureas Altering the prescribed dose through cutting or splitting makes it impossible for healthcare providers to accurately assess whether adverse effects are dose-related and how to appropriately adjust therapy
