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In summary, although the two neurons did not die of GPX4 reduction, the study focused on only one point of GPX4 and did not delve into other regulators, indicating that there are other pathways affecting the activity of POMC neurons under obesity conditions ( Immunomodulation with obesity and ferroptosis With the continuous in-depth study of obesity, the importance of AT immune cells as a key hub for regulating the AT environment has become recognized