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This section covers the interaction patterns that matter most for GLP-1 therapy

After withdrawal of the needle, the area was swabbed to remove any excess tracer

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Genes encoding the glucagon ( Gcgr ), GLP-1 ( Glp1r ), and GLP2 ( Glp2r ) receptors are all reactively closely related G protein-coupled receptors that originated via gene duplication events near the origin of vertebrates ( Gcgr ), glucagon-like peptide-1 ( Glp1r ), glucagon-like peptide-2 ( Glp2r ), and glucose-dependent insulinotropic peptide ( Gipr ) receptor genes in diverse vertebrates suggested that Glp1r had experienced the strongest purifying selection ( Gcgr , Glp1r , and Glp2r experience significantly different levels of selection pressure (as measured by d N /d S ratios), with Glp1r experiencing the stronger purifying selection, Glp2r the least, and Gcgr an intermediate amount (73), which calculates d N /d S ratios on specific lineages, to test for intensification or relaxation of selective constrains between sets of receptor coding sequences