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Moreover, consuming sugary snacks and processed foods can lead to leptin and insulin resistance

"Obesity is a chronic condition and thus requires long-term treatment," says Shalev, who believes the field is moving toward a two-step approach: using a GLP-1 to achieve weight loss, followed by a different medication to help maintain it

Sarcopenia (muscle loss) due to rapid weight loss if measures to preserve muscle are not taken, including regular strength training, staying active, and eating a protein-rich diet

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