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Its effects on fat are indirect: better nutrient partitioning, improved insulin sensitivity, and increased energy expenditure from greater muscle mass
Microbiotadependent metabolite trimethylamineNoxide is associated with disease severity and survival of patients with chronic heart failure
The distinction is clinically important : if gout occurs due to weight loss rather than a direct drug effect, the long-term benefits of sustained weight reduction would likely outweigh temporary risks, as obesity itself is a significant risk factor for developing gout
Expect more to emerge over the next few years due to more use
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