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Due to the presence of multiple double bonds in their molecular structure, PUFAs exhibit heightened susceptibility to oxidation, rendering them a primary target for lipid peroxidation (114, 115)

While many patients experience improvement in symptoms over weeks to months of continued therapy, the timeline for resolution varies considerably between individuals

The FOXO4 factor is considered to regulate various cell pathways, including insulin signaling, cell cycle progression, and other functions that regulate growth and differentiation

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