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And in the short term, it can help you feel warmer

The DIO3 gene codes for D3, which is detected in brain, skin, liver, intestine, placenta and pregnant uterus, where it catalyzes the inactivation of T4 and T3

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Notably, GLP-1Rs in circumventricular organs are targets for peripheral GLP-1, particularly after large meals or under conditions like rapid gastric emptying (Holst, Reference Holst2024)