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The most frequently reported issues include nausea, constipation, headache, dizziness, insomnia, and dry mouth

Based on these results of viability, the concentration of PS-MP to be tested in all further experiments were 100 g/mL, as it was not only inducing viability reduction, but the increased tendency observed caught our attention

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Declarations Acknowledgement The authors acknowledge the technical assistance of Prof Ngwu Nwachukwu of the Department of Biochemistry, School of Biological Sciences, Federal University of Technology, Owerri, Imo State, Nigeria