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113 In the canonical Wnt/-catenin pathway, the protein destruction complex (adenomatous polyposis coli [APC], casein kinase 1 [CK1], glycogen synthase kinase 3 [GSK-3], and axis inhibition proteins [AXINs]) targets and phosphorylates the -catenin protein

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Exposure to xenobiotics, heavy metals (such as lead, mercury, and arsenic), stress, poor dietary choices, toxic cocktails of prescription and non-prescription drugs, trauma, and infections all have huge consequences for the body and its ability to maintain adequate glutathione levels