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For example, Motus (oral) reported about 10.4 percent average weight loss in human clinical trials over six months, which is notable for a supplement and compares favorably with some lower-dose pharmaceutical outcomes

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| 1 Youre not in a calorie deficit | 2 Youre in a weight-loss plateau | 3 Your current dose isnt high enough to promote lower hunger | Practical strategies | Frequently asked questions | Take home message The main reasons youre not losing weight on semaglutide (Wegovy/Ozempic) might be that youre not eating in a calorie deficit, youve hit a weight-loss plateau, or the current dose that youre on isnt high enough to lower your hunger to the point where youre eating less