A number of positive anti-inflammatory actions of thiamine include activation of Nrf2 and decreased ROS levels, enhanced activity of mitochondrial respiratory chain complexes I-IV, downregulation of endoplasmic reticulum stress, and suppression of gene expression associated with mitophagy, oxidative stress, and proinflammatory cytokines (205)
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Thus, in a cohort of 235 ASD patients, the 7q32 region, a candidate ASD region, was investigated [85]
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