Dave Knapp Nov 12, 2024 4 min read If you've been following the news on GLP-1 medications like Ozempic and Wegovy, you've likely noticed their manufacturer Novo Nordisk, has a lot to say about the risks of compounded semaglutide
The enzyme activities of COXs were determined spectrophotometrically by monitoring the oxidation of N,N,N,N -tetramethyl- p -phenylenediamine (TMPD) at 610 nm during the conversion of PGG 2 to PGH 2
Oridonin, a diterpenoid compound isolated from Rabdosia rubescens , was shown to alleviate PI-IBS symptoms in rats by significantly inhibiting phosphorylation of NF-B p65 and downregulating downstream inflammatory mediators such as inducible nitric oxide synthase (iNOS), COX-2, IL-1, and IL-6
There isn't independent clinical data provided here confirming added benefit from these additions in this formulation, so treat it as a bonus rather than a proven feature