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Get some tea and settle in, its a long one My personal experience with low-dose semaglutide (GLP-1) in Perimenopause, and why I think this conversation needs way more nuance: Okay, so over the last couple of years (as I moved deeper into my mid-40s) I started noticing something that so many women tell me about but hardly anyone talks about honestly: My appetite changed

Tirzepatide is a dual GLP/GIP agonist, while semaglutide is only a GLP-1 agonist

Besides its effects on glucose homeostasis, semaglutide also lowers energy intake and induces remarkable weight loss [1], [4]