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Certain risk factors for gout include being overweight and consuming food and drinks with lots of purines, such as red meat and alcohol

Ann Trop Med Parasitol (1991) 85:41725

My only hesitation in accepting the hypothesis that obesity is a downstream effect of hypothalamic inflammation lies in the fact that, in metabolically healthy individuals, a normally functioning digestive system, a non-steatotic liver, nutrient-sensitive pancreas and intestine, insulin-sensitive adipose tissue, should mitigate, at least to some extent (though not completely), the negative effects of an unhealthy diet, until their compensatory capacity fails

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