SIRT6 mitigates heart failure with preserved ejection fraction in diabetes
The study authors found 107 reports of patients, out of more than 30,500 total, who said they thought about killing themselves while taking semaglutide and 162 similar reports, out of more than 52,000, in patients taking liraglutide, a different injected diabetes medication thats in the same class as semaglutide
For individuals considering starting or already on a weight loss journey, knowing these signs and having open communication with your care team is paramount
You should contact your GP or healthcare provider if you experience any of the following: Two or more consecutive missed periods without an obvious explanation Sudden cessation of previously regular cycles , particularly if accompanied by other symptoms Severe pelvic pain, abnormal vaginal bleeding, or discharge (seek same-day assessment via NHS 111, urgent GP appointment, or Early Pregnancy Unit if pregnancy is possible) Signs of pregnancy such as nausea, breast tenderness, or fatigue Symptoms suggesting hormonal imbalance , including excessive hair growth, acne, or significant mood changes Unintentional weight loss exceeding clinical targets or signs of malnutrition If you have severe abdominal pain with a positive pregnancy test or heavy bleeding, seek urgent medical care through A&E or call 999