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The data shows psychiatric benefits beyond weight loss, including anti-inflammatory effects that directly benefit mood

In addition, these studies have been based on the relative taxonomic composition of the microbiota, so they lack information on gene composition and functional capacity of the gut microbiome

It may develop secondarily to HIV-induced cytokine dysregulation, to medications used in the treatment of HIV infection or HIV-associated diseases (zidovudine, clofazimine and ketoconazole), or to adrenocortical deficiency, which is not infrequent in HIV-seropositive subjects with a low CD4+ T cell counts [6, 10]

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