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10.1016/j.pharmthera.2021.107916 87 PettieJ

Zone 2 Training Moderate-intensity cardiovascular exercise improves mitochondrial function and supports hormone balance without overstressing the system

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Bulk RNA sequencing revealed that gene expression changes were most pronounced in the MBH, where RAMP1/3 KO mice treated with sCT showed extensive differential expression of over 1,700 genes, while WT mice exhibited comparatively minor transcriptional shifts