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Tirzepatide, marketed as Zepbound for weight loss and Mounjaro for diabetes, faces a different patent landscape

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Mechanistically, the degradation of ARNTL/BMAL1 leads to the upregulation of EGLN2 (hypoxia-inducible factor 2) and subsequently suppressing the function of HIF1A (hypoxia-inducible factor 1 subunit alpha)

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, Zhu, J

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