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In order to generate this model and induce PCOS-like traits in adult offspring, pregnant dams were administered with a daily dose of the androgen dihydrotestosterone (DHT, 250 g/day) during gestational days 16, 17, and 18

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This enabled us to assess whether the structural differences and conformational dynamics observed in the Cagri and rAmy bound AMYR structures alter the nature of Gs protein interaction (Supplementary Fig