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The pain and swelling are due to the friction between bones caused by loss of cartilage and inflammation of the ligaments, tendons, or synovial membrane covering the joint cavity

DOI: 10.1080/10408398.2021.1959295 16

1 Introduction Cynanchum plants have been used to treat a variety of diseases in folk medicine, such as cancer, inflammation, and viral infections ( 21 sterol glycosides, a class of secondary metabolites in Cynanchum plants, are responsible for regulating cellular activities associated with cancer, including cell proliferation, apoptosis, and metastasis ( 21 steroidal glycosides (e.g., dioscin) can have potent anticancer activity by triggering mitochondrial apoptosis, caudatin is structurally unique given its incorporation of an isovalerate side chain and the C-3 glycosylation affords a broader target specificity against Wnt/-catenin and autophagy-lysosomal pathways

One such compound that has gained considerable attention in recent years is glutathione