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The application of engineered cell strains with special plasmid vectors that encode fusion proteins helps to develop targeted exosome-based delivery systems by achieving amenable membrane modifications and desirable attributes especially when targeting a specific cell type (Farooqi et al., 2018)

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In rats, DSIP and a related analogue reduced seizure-related activity in a chemically induced seizure model, but this does not demonstrate improved memory or cognition in humans [12]