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It is important to note that GLP-1 receptor agonists are not FDA-approved specifically for the treatment of MASLD or MASH, though they may be used off-label in appropriate patients

Reasons for discontinuation of obesity pharmacotherapy with semaglutide or Tirzepatide in clinical practice

Specifically, the method comprises the following steps: arg34GLP-1 (9-37) carries out the modification of the terminal amino group: 1g Boc-His (Boc) -Aib-OH was dissolved in 10mL of dichloromethane and 0.37g DIC was added