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Grape seed-derived procyanidins have an antihyperglycemic effect in streptozotocin-induced diabetic rats and insulinomimetic activity in insulin-sensitive cell lines

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The STEP and SURMOUNT trials demonstrated that these GLP-1 receptor agonists and GLP-1/GIP receptor agonists produce average weight losses of 1522% body weight over 68 weeksfar exceeding any published probiotic data