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B12 deficiency can also lead to the destruction of immature red blood cells in the bone marrow, which can cause jaundice (yellowing of the skin and whites of the eyes)

Consistent with our final ASC payment policy, for the CY 2017 ASC payment system and subsequent years, in the CY 2017 OPPS/ASC final rule with comment period (81 FR 79751 through 79753), we finalized our policy to calculate and apply a budget neutrality adjustment to the ASC conversion factor for supplier-level changes in wage index values for the upcoming year, just as the OPPS wage index budget neutrality adjustment is calculated and applied to the OPPS conversion factor

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Beyer L, Batsikadze G, Timmann D, Gerwig M