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To put that in perspective, a 10 mg/kg dose in a 250-g rat, scaled allometrically to a 70-kg human using the FDA's body surface area conversion factor of 6.2, translates to roughly 1.6 mg/kg, or 112 mg for a 70-kg person 7

Here's the honest version, because you deserve it: 5-Amino-1MQ is not an overnight fix, and anyone promising a specific number on the scale by a specific date is guessing

A poorly reconstituted vial can introduce inconsistencies in concentration from one draw to the next, which undermines the reliability of any research built on it

Metabolic pathway requiring 5-deoxyadenosylcobalamin The figure illustrates the metabolic pathway for the vitamin B 12 -dependent enzyme L-methylmalonyl-CoA mutase, which converts L-methylmalonyl-CoA into succinyl-CoA for entry into the citric acid cycle