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It also increases your insulin resistance, a condition where your body becomes less responsive to insulin, the hormone responsible for directing your body to use sugar for energy

doi: 10.5653/cerm.2021.04560

While technically zero-calorie, some artificial sweeteners can provoke a cephalic phase insulin response in some individuals

It was FDA-approved in 2010 as a weight loss medication for Netherlands HIV patients suffering from lipodystrophy, a condition that leads to an accumulation of fat (adipose tissue) in the abdominal area