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Related incretin-based medicines you might hear about include tirzepatide (Mounjaro for type 2 diabetes, and Zepbound for chronic weight management), a dual GIP/GLP-1 receptor agonist given as a once-weekly injection

Second, it was conducted in postmenopausal women with already-reduced bone density - not in women actively undergoing rapid weight loss or GLP-1 therapy

Additionally, a Mendelian randomization study showed that the a allele of IGFBP 3 SNP rs2854744 is associated with increased levels of circulating IGFBP 3 and decreased BrCa risk [65]

Studied for actin sequestration, cell migration, and angiogenesis in preclinical models