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There is no clinical data on this combination, and it is generally not recommended because the GLP-1 receptor activation from multiple compounds would overlap, potentially increasing gastrointestinal side effects without proportional benefit

The various products of such enzymes in the microbiome of the human gut are currently of great interest, as they have the potential to impact host immunity and metabolic responses

The following populations have no published exposure data and would generally be excluded from research-context use: - People who are pregnant, trying to become pregnant, or breastfeeding