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Site 1 is a structural site which is nearly always occupied by Zn II , whose integrity stabilizes the dimer

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Polyunsaturated fatty acids tend to form free radicals upon exposure to oxygen and this may lead to an increased risk of certain cancers

Food and Drug Administration approved treatment for APAP induced liver injury ( in vitro and in vivo as possible alternative treatments for APAP induced liver injury ( 2 Effects and mechanism of natural products in acetaminophen-induced hepatotoxicity A number of phytochemicals have been identified to have hepatoprotective activity, such as silymarin for the treatment of liver poisoning, chronic hepatitis and cirrhosis (Table 1)