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however, the underlying mechanisms are uncertain, due to the fact that some TH actions on glucose tolerance and insulin sensitivity in different tissues may have divergent influences on blood glucose levels 35
Naltrexone has a more positive safety profile but faces significant obstacles in treatment initiation for OUD
Figure 6: Photograph of Sir Frederick Banting and Charles Best with dog 408 taken in August 1921 by Henry Mahon on the roof of the University of Torontos Medical Building
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