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Archived from the original on 4 November 2014

Several factors may indicate its time to consider discontinuation: Stable health improvements: Some individuals achieve significant weight loss, improved glycemic control, or normalized blood pressure and lipid levels, which may reduce the clinical need for continued medication

This higher dose provides a treatment intensification option for patients with type 2 diabetes treated with semaglutide in need of additional glycaemic control

The recommended approach for dosage and administration of Calocurb is to start with a lower concentration, typically one pill (125 mg), and gradually increase the dosage over a series of days until the desired appetite suppressing effect is achieved